Volume 31 Number 1 (2022)

Evaluation of the Status of Glycated Haemoglobin in Male type 2 Diabetic Patients

Mumu NS1 , Nessa A2 , Rahman S3 , Meherubin I4 , Yeasmin F5 , Afroz L6

Mymensingh Med J 2022 Jan; 31 (1): 37-40

PMID: 34999677

Abstract

The incidence of type 2 diabetes mellitus is increasing in Bangladesh with its attendant complications. Glycated haemoglobin (HbA1c) is broadly used as an index of mean glycaemia. This study was planned to evaluate the status of glycated haemoglobin (HbA1c) in male type 2 diabetic patients. This cross-sectional analytical study was executed in the Department of Physiology, Mymensingh Medical College, Mymensingh, Bangladesh from July 2019 to June 2020. This study included in total 200 male subjects who are above 40 years in age. Among them, one hundred (100) male type 2 diabetic patients were taken as study group (Group I) and one hundred (100) age matched healthy male subjects were taken as control group (Group II). Glycated haemoglobin was assessed by ion-exchange high performance liquid chromatography (HPLC) method. Mean±SD was used to express data and unpaired Student’s ‘t’ test was used to calculate the statistical significance of difference amongst the groups. Pearson’s correlation coefficient test was done to correlate the relationship between serum fasting glucose and glycated haemoglobin. The mean±SD of fasting serum glucose of Group I and Group II were 9.79±2.88mmol/L and 5.23±0.48mmol/L respectively. The mean±SD of glycated haemoglobin of Group I and Group II were 8.38±1.28mmol/L and 5.19±0.46mmol/L respectively. The mean±SD of glycated haemoglobin is found to be significantly higher in the study group compared to the control group and there is a positive correlation between fasting serum glucose and glycated haemoglobin. So, routine estimation of this parameter (HbA1c) is important for prevention of complications related to type 2 diabetes mellitus for leading healthy life.

Keywords: Type 2 diabetes mellitus, Glycated haemoglobin, Fasting serum glucose


  1. Assistant Professor

    Department of Physiology, President Abdul Hamid Medical College, Kishorganj, Bangladesh

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Volume 31, Number 1 (2022)
Page: 37-40