Volume 34 Number 4 (2025)
Association of Depressive Symptoms with Glycemic Control and Diabetic Complications in Patients with Type 2 Diabetes Mellitus: A Facility-Based Cross-Sectional Study in Bangladesh
Hossain MS1 , Hassan K2 , Laboni R3 , Ashrafuzzaman SM4 , Tabassum M5 , Rafi MA6 , Hasan MJ7
Mymensingh Med J 2025 Oct; 34 (4): 1125-1132
PMID: 41024551
Abstract
Comorbid depressive symptoms in diabetic patients may be associated with metabolic deterioration. The objective of this facility-based cross-sectional study was to determine the prevalence of depressive symptoms and their association with glycemic control and diabetic complications among patients with type 2 diabetes mellitus (T2DM) in Bangladesh. This study was conducted among 350 patients with type 2 diabetes mellitus attending the outpatient department of the Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka Bangladesh, from July 1, 2021 to July 31, 2021. The prevalence of depressive symptoms was 31.0% (mild 10.0%, moderate 12.0%, moderately severe 5.1% and severe 4.0%). In the logistic regression model, age (aOR 1.11, 95% CI 1.01-1.22), female sex (aOR 2.47, 95% CI 1.22-5.00), rural residence (aOR 3.42, 95% CI 1.82-6.45), single living (aOR 7.34, 95% CI 5.51-9.63), poor glycemic control (aOR 2.59, 95% CI 1.31-5.12) and cardiovascular complications (aOR 4.17, 95% CI 1.36-12.78) were independent predictors of depressive symptoms among T2DM patients. The findings observed from this study support an association between depressive symptoms and poor glycemic control as well as cardiovascular complications of diabetes.
Keywords: Type 2 diabetes mellitus, Depression, Glycemic control, PHQ-9, Bangladesh
- Resident Medical Officer (RMO)