Volume 31 Number 2 (2022)
Age Related Changes in the Purkinje Cells in Human Cerebellar Cortex in Bangladeshi People
Sultana N1 , Imtiaz M2 , Ferdaus F3 , Raihan MM4 , Azad S5 , Kabir A6 , Sultana N7 , Jabeen L8 , Sumi SA9 , Khan NJ10 , Farjan S11
Mymensingh Med J 2022 April; 31 (2): 416-420
PMID: 35383760
Abstract
This study was done to see the changes in the number of Purkinje cells per square mm in different age groups of Bangladeshi people. This cross-sectional descriptive type of study was done on total 40 postmortem human cerebellums, in the Department of Anatomy, Mymensingh Medical College, Bangladesh from July 2016 to June 2017. The specimens were collected from morgue in the department of Forensic Medicine, Mymensingh Medical College, by purposive sampling technique. All the specimens were grouped into four categories: Group A (20 to 29 years), Group B (30 to 39 years), Group C (40 to 49 years) and Group D (50 to 59 years). Paraffin blocks of cerebellum were cut at 4-5µm thickness and stained with routine “Haematoxylin and Eosin” (H & E) stain. Estimation of number of Purkinje cell was done by using the counting circle and examined under the light microscope. In the present study, the mean±SD number of Purkinje cell was found 128.67±25.15 per sq mm in Group A, 136.53±34.45 in Group B per sq mm, 135.55±29.44 per sq mm in Group C, 127.69±35.31 per sq mm in Group D.
Keywords: Cerebellum, Purkinje cell, Number, Bangladeshi people
- Assistant Professor